... 100% natural, extracted by water and ethanol, no residue solvents.Diacerein(4,5-bis(acetyloxy)-9,10-dioxo-2-anthracene carboxylic ... conventional forms of drug therapy.Clinical trials have shown tha diacerein is highly effective in relieving the symptoms of osteoarthritis. ... of osteoarthritis.In many in vitro models, therapeutic levels of diacerein and rhein, its active metabolite, have been shown to ...