... .Simvastatin Systematic (IUPAC) name(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2 ... -yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoateClinical dataTrade namesZocorAHFS/Drugs ... Protein binding95%MetabolismHepatic (CYP3A4)Half-life2 hours for simvastatin and 1.9 hours for simvastatin acidExcretionRenal 13%, faecal 60%IdentifiersCAS ...