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1.Thiocolchicoside
2.CAS:602-41-5
3.M.F.:C27H33NO10S
4.Appearance;White or light yellow powder
5.Purity:99.0%
Product Name | Thiocolchicoside | ||
Appearance | Light yellow crystal Powder | Odor | Characteristic |
Part of used | Corm | Molecular Formula | C22H25NO6 |
Purity | 98% HPLC | ||
Standard | USP/BP | ||
Function | Main functions are as follows: 1. Anti-cancer 2. Anti-gout 3. Cure chronic hepatitis and cirrhosis of liver | ||
Applications | Thiocolchicoside Main applications are as follows: Thiocolchicoside widely used in pharmaceutical, functional food | ||
Packing | 25kg/drum, inner double plastic bag or according to customers requirement. | ||
Shelf Life | 2 years | ||
Storage | Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation. | ||
Thiocolchicoside
Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It acts as a competitive GABAA receptor antagonist and also inhibits glycine receptors with similar potency and nicotinic acetylcholine receptors to a much lesser extent. It has powerful convulsant activity and should not be used in seizure-prone individuals.
Thiocolchicoside, a semi-synthetic derivative of the naturally occurring compound colchicoside extracted from the seeds of Gloriosa superba..Its Chemical name is N-[1,2-dimethoxy-10-methylsulfanyl-9-oxo-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,7-dihydro-5H-enzo[d]heptalen-7-yl] acetamide and molecular formula C27H33NO10S .
Thiocolchicoside is a Yellow crystalline Powder, soluble in water & alcohol.
Source
Thiocolchicoside is extracted from the seeds of Gloriosa Superba.
Gloriosa is a genus of five or six species in the plant family Colchicaceae, from tropical Africa and Asia. They are tender, tuberous rooted deciduous perennials, adapted to summer rainfall with a dormant dry season. Their native range is Africa, Southeastern Asia and parts of Malaysia, but they are now widely cultivated.
Gloriosa superba is the national flower of Zimbabwe, former Rhodesia (where it is a protected plant). It is also the state flower of Tamilnadu state in India.
Product Name: | Thiocolchicoside |
Synonyms: | (S)-N-(5,6,7,9-TETRAHYDRO-1,2,3,10-TETRAMETHOXY-9-OXOBENZO[A]HEPTALEN-7-YL)ACETAMIDE;N-((S)-1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL)-ACETAMIDE;n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-acetamide;7-acetamido-6,7-dihydro-1,2,3,10-tetramethoxy-benzo(a)heptalen-9(5h)-on;7-alpha-h-colchicine;7alpha-h-colchicine;7alphaH-Colchicine;Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(alpha)heptalen-7-yl)- |
CAS: | 64-86-8 |
MF: | C22H25NO6 |
MW: | 399.44 |
EINECS: | 200-598-5 |
Product Categories: | Alkaloids;All Inhibitors;Alkaloids (Others);Biochemistry;Plant Growth Regulators;Plant Growth Trgulators (Others);Tropolones;Tropolones & Azulenes;Antibiotic Explorer;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Antitumor Agents;Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Microtobule InhibitorsCancer Research;Microtubule Inhibitors;Caspases/Apoptosis;Amines;Chiral Reagents;Heterocycles |
Mol File: | 64-86-8.mol |
mp | 150-160 °C (dec.)(lit.) |
alpha | -250 º (c=1, alcohol) |
storage temp. | Poison room |
solubility | H2O: 10 mg/mL |
form | powder |
color | white to yellow with a green cast |
Water Solubility | 45 g/L (20 ºC) |
Sensitive | Light Sensitive |
Merck | 14,2471 |
BRN | 2228813 |
Stability: | Stable. Light sensitive. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 64-86-8(CAS DataBase Reference) |
NIST Chemistry Reference | Colchicine(64-86-8) |
EPA Substance Registry System | Acetamide, N-[(7S)-5,6,7,9-tetrahydro- 1,2,3,10-tetramethoxy-9-oxobenzo[ a]heptalen-7-yl]-(64-86-8) |
Thiocolchicoside