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[Product name] Berberine sulfate
[Appearance]Orange yellow crystalline powder
[Loss on drying]≤15%
[Specification]98% (uv)
[Executive standard]Chinese Pharmacopoeia
[Packing]25KG/ drum
Other introduction:
Raw material name:Cortex Phellodendri Chinensis
CAS No:316-41-6
Part used: tree bark
Active Ingredient: Berberine sulfate
Molecular Formula:(C20H18O4N)2SO4
Molecular Weight: 768.84
Test Method: uv
Size: 80 Meshes
[ pharmacological ]
The Chinese medicine refined broad-spectrum long-acting antibacterial drugs. Inhibition effect on many kinds of Gram-positive bacteria and Gram-negative bacteria have antibacterial effects on both, hemolytic streptococcus, Bacillus dysenteriae, Salmonella, Salmonella, Pasteurella multocida, Escherichia coli, Staphylococcus aureus, Freund, Shigella dysenteriae, and increased leukocyte phagocytosis, also have inhibitory effect different degrees of Mycobacterium tuberculosis, plague, also has antipyretic effect and antiarrhythmic effect. The main for the bacterial virus caused intestinal infection, acute and chronic gastroenteritis, diarrhea, more than jiuxie, malignant diarrhea, clostridial enteritis, seasonal diarrhea, all kinds of pyogenic infection.
The oxidation process of berberine sulphate can inhibit pyruvate glucose metabolism in bacteria, bacterial effects on vitamin B6, use of nicotinamide, synthesis of DNA, RNA, inhibition of bacterial protein and lipid, but also the formation of complexes with DNA, effects of DNA replication, inhibition of reproduction. In addition, but also enhance the ability of leukocyte phagocytosis of Staphylococcus aureus, but to enhance the ability of network makeup endothelial system, on the bacterial toxin and detoxification effect is obvious, immune enhancer. And the intestinal production of indole, methyl indole harmful substances such as enzyme antagonism, curb corruption in fermented sausage. To promote the generation of cat and dog liver bile, and secretion.
Berberine sulfate oral absorption, absorption can quickly into the heart, lung, liver, kidney and other tissues, the blood concentration is low. In vivo by most of the liver metabolism excreted by the kidneys, only a small part of the prototype from the urine.
Berberine sulphate resistance of amoeba effect in both in vitro and in vivo, in vitro effect is equivalent to the 1/128 and the emetine and tetrandrine on 1/4, the in vivo effect is equivalent to tetrandrine 1/16.
Berberine sulfate 0.1-6.0mg/kg intravenous injection, can make the anesthetized dogs, cats, rats, blood pressure.
Berberine sulfate 1-3mg/ml test in vitro, can reduce the heparin (50u/ml ) on human and canine blood anticoagulant effect of berberine, but 10mg/ml alone, itself has anticoagulant effect.
Because the human body has large amount of chloride ion, but no sulfate ion, chlorine ion of berberine hydrochloride in normal human, and sulfate berberine sulfate are harmful to the human body, so the berberine sulfate can generally used for veterinary drugs.
Package & Storage:
1. Packing: by 25kgs/drum,inner by double plastic bags
2. Stored in cool and dry well-closed container, keep away from moisture and strong light/heat.
Pure natural Berberine sulfate