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-Produt name:Caffeic Acid
-CAS#:331-39-5
-Specification:99%
-Appearance:Yellow crystalline powder
Caffeic Acid
| Product name | Caffeic Acid | Brand name | Realin |
| CAS# | 331-39-5 | Appearance | Yellow crystalline powder |
| Specification | 99% | Solubility | Soluble in water |
| Molecular formula | C9H8O4 | Molecular weight | 180.16 |
| Melting point | 195.0-198.0°C | Molecular structure | |
| Function | Caffeic acid has been shown to inhibit carcinogenesis, although other experimentsshow possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo. Caffeic acid also shows immunomodulatory and anti-inflammatory activity. Caffeic acid outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance.Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti- fungicide methods by supplementing trees with antioxidants.Another study also showed that CAPE suppresses acute immune and inflammatory responses and holds promise for therapeutic uses to reduce inflammation. | ||
| Shelf Life | Two years | ||
| Storage | Store in cool & dry place, Keep away from strong light and heat. | ||
Packaging:
1kg with double plastic container inside/Aluminum foil bag outside.
25kg with double plastic container inside/Fiber drum outside.
Beneficial Uses
Oral administration of high doses of caffeic acid in rats has caused stomach papillomas, leading tothe perception of caffeic acid as carcinogenic. In the same study, only highdoses of combined antioxidants, including caffeic acid, showed a significantdecrease in growth of colon tumors in those same rats. No significant effectwas noted otherwise.
Caffeic Acid is stilllisted under older Hazard Data sheets caffeic acid as a potential carcinogen because oftwo early experiments on rats and mice.
More recent data show thatbacteria in the rats' guts may alter the formation of metabolites of CaffeicAcid. There have been no known ill-effects of Caffeic Acid in humans.
Caffeic Acid and itsderivative, Caffeic Acid Phenethyl Ester (CAPE) have shown tumor-shrinkingproperties. When an anti-cancer drug was being sought, Caffeic Acid and CAPEwere derived from Burning Bush (Euonymus alatus). "The subcutaneous andoral administrations of CA and CAPE significantly reduced liver metastasis.These results confirm the therapeutic potential of the compounds and suggestthat the anti-metastatic and anti-tumor effects of CA and CAPE are mediatedthrough the selective suppression of MMP-9 enzyme activity and transcriptionaldown-regulation by the dual inhibition of NF-B as well as MMP-9 catalyticactivity."
A study using the caffeicacid phenethyl ester (CAPE) showed a positive effect on reducing carcinogenicincidence. Caffeic acid phenethyl ester (CAPE) is an active component ofpropolis from honeybee hives.it is known to have antimitogenic,anticarcinogenic, anti-inflammatory, and immunomodulatory properties.
natural organic caffeic acid in bulk supply