Chemical Name and othernames

CAS Number

123-99-9

Molecular Formula

C9H16O4

Molecular Weight

88.22

Molecular Structure

Packing

25kg/drum

Capacity

Production upon order

Storage

Keep tightly closed in light-resistant containers.

Application

Azelaic acid topical antimicrobial agent to inhibit and kill a variety of aerobic and anaerobic bacteria on the skin, topical 20% azelaic acid cream can significantly reduce skin bacteria Propionibacterium acnes, and follicular bacterial growth and the decline in the free fatty acid content of the skin surface lipids. Antimicrobial activity and absorption of the goods, and are dependent on the pH, low pH, having a high antibacterial activity, faster into the cell has a good antibacterial effect, the skin diseases caused by a variety of different causes. Is permeable to drugs than normal cells of the abnormal cells, the main activity of the enzyme can be reversibly inhibited. Inhibition of protein synthesis, with the mechanism of action of other fungicides and bacteriostatic agents.The goods on normal skin and acne infected skin anti-keratinization role, its mechanism is to reduce follicular hyperkeratosis.This product also has anti-proliferative and anti-cytotoxic effect, this seems to be by disrupting mitochondrial respiration and DNA synthesis, rather than inhibit the activity of tyrosinase. UV structural studies have shown that when the in vitro skin or choroidal melanoma cells or skin biopsies from patients with malignant small mole or skin melanoma patients placed the azaleas acid (≤ 100nmol / L), appear to have the apparent selectivity mitochondrial swelling, formation of vacuoles and the of cytoplasmic lipid particles aggregation phenomenon. Reduce pigmentation and reduce the size of the black spot damage, 20% of the goods with 4% hydroquinone cream quite significantly better than 2% hydroquinone ointment. This product of mild to moderate acne patients can significantly reduce the number of comedones, papules and pustules