1.pvp-p properties
Pvpp is white to creamy white, free-flowing powder, easily hygroscopic, insoluble in water, acid, alkaline and all other common solvents; swells rapidly in water without forming a gel; better flow ability and plasticity, strong particle compressibility, non-ionic , chemically inert.
2.pvp-p specification
PH value ( 1% s suspension in water ) | 5-8 |
Water-soluble substances ,%l | ≤0.5 |
Loss on drying,% | ≤6.0 |
Sulphated ash | ≤0.4 |
Free N-vinylpyrrolidone ppm | ≤10 |
Free N,N-Divinyl-imidazolidone ppm | ≤2 |
Heavy metals as lead ,ppm | ≤10 |
Arsenic ppm | ≤2 |
Assay,as Nitrogen content % | 11.0-12.8 |
3.pvp-p application
1).Due to its excellent swelling characteristics in water, can be used as water insoluble tablet disintegrating agent for wet and dry granulation and direct compression processes in tablets whether added before or after granulations. It exhibits high capillary activity and pronounced hydration capacity, barely forming gels
2).Solubility enhancer, increasing the solubility of poorly soluble drugs by co-evaporation.
3).Suspension stabilizer, increasing the viscosity, improving the dispersal capacity, reducing the sedimentation rate of drug, meanwhile increasing the redispersibility of the solution sediment, suitable for liquid preparations and oral instant disintegrating preparations
4).complextant agent of drug ingredients, stabilizing active ingredients in pharmaceutical products, improving their solubility and bioavailability
5).Be used as stabilizer for beer, wine, cinegar and many juice and beverage to prolong their storage life
4.pvp-p packaging and storage
Packed in 20kg fiber plastic drum, inner lined with PE bags
Stored in a dry place at room temperature.
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